What are the processes that give rise to mutations throughout life in every cell of the body? Can these somatic mutations be used as a molecular tool to reveal the origins of brain tumors and other brain diseases directly in humans? And can newly developed genomics technologies be deployed more rapidly and reliably in clinical medicine?

Our mission is to develop foundational new technologies for human genetics and neuroscience that will advance our understanding of somatic mutations and diseases of the brain. We also aim to accelerate the implementation of genomics in clinical medicine, especially for children with rare undiagnosed diseases.